Estimation of Glomerular Filtration Rate from Plasma Clearance of 51-Chromium Edetic Acid

Estimation of glomerular filtration rate from plasma clearance of 51-chromium edetic acid.

Chantler, C., and Barratt. T. M. (1972). Archives of Disease in Childhood, 47, 613. Estimation of glomerular filtration rate from plasma clearance of 51-chromium edetic acid. The glomerular filtration rate was estimated by a single compartment analysis of the rate of fall of plasma concentration of 51-chromium edetic acid after a single intravenous injection. This slope clearance consistently o...

Estimation of glomerular filtration rate from height/plasma creatinine ratio.

Estimation of glomerular filtration rate from the serum creatinine concentration.

In patients with renal failure the dose of renally excreted drugs should be reduced in proportion with the degree of impairment of glomerular filtration: in this situation it is appropriate to measure the glomerular filtration rate in order to determine accurately the correct dose. However, as 24 hour urine based creatinine clearance measurements are time consuming and inaccurate, the parameter...

Estimation of glomerular filtration rate from plasma creatinine concentration in children of various ages.

The relation between the true plasma creatinine concentration (Pc) and the glomerular filtration rate corrected for body surface area (GFR/SA) was investigated in 108 individuals, and the following formula was derived: GFR/SA (ml/min per 1-73m2SA) = 0-43 Ht (cm)/Pc (mg/100 ml). This formula was tested in a second group of 83 children, and its accuracy and precision was compared to the 24-hour c...

Inaccuracy of glomerular filtration rate estimation from height/plasma creatinine ratio.

Use of a height/plasma creatinine formula to estimate glomerular filtration rate (GFR) is simpler and less invasive than renal or plasma clearance methods. The aim of this study was to determine whether these formulas enabled accurate prediction of GFR measured from the plasma clearance of 51Cr labelled ethylenediaminetetra-acetic acid (51Cr-EDTA). Thirty nine patients underwent GFR measurement...